DeepRx COLOXIS. A first-of-the-class AI clinical decision system for predicting oxaliplatin benefits in GI cancers.
Tumor-specific causal inference. A patent technology called tumor-specific causal inference (TCI) for revealing genomic causes of each tumor using (US Patent awarded)
DeepRx IO. An AI system for discovering tumor-specific intercellular communication networks using single-cell sequencing, spatial sequencing, and instance-specific Bayesian causal network learning.
DeepRx GI: An AI system for guiding pan-gastrointestinal cancer therapies. Trained with data from thousands of patients from rigorous clinical trials, the system recommends optimal combination regimens for treating GI cancer patients.
DeepRx BRCA. An AI system for guiding pre-operation chemotherapies for breast cancer patients to increase the chance of reducing tumor burden and success of operation.
Chen, L, Wang, Y, Cai, C, Ding, Y, Kim, RS., Lipchik, C, Gavin, PG., Yothers, G, Allegra, CJ, Petrelli, NJ, Suga, JM., Hopkins, JO., Saito, NG., Evans, T., Jujjavarapu, S., Wolmark, N., Lucas, PC., Paik, S., Sun, M., Pogue-Geile, KL., Lu, X. (2023) Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer. Journal of Clinical Oncology Epub:JCO2301080. doi: 10.1200/JCO.23.01080
Ding, MQ., Chen, L., Cooper, GF., Young, JD., and Lu, X. (2017) Precision oncology beyond targeted therapy: Combining omics data with machine learning matches the majority of cancer cells to effective therapeutics. Molecular Cancer Research 16(2):269-278